Synthesis and anticancer activity novel dimeric azatriperoxides
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چکیده
منابع مشابه
Synthesis and anticancer activity assay of novel chalcone sulfonamide derivatives
Chalcones, or 1,3–diaryl–2–propen–1–ones, one of the major classes of natural products and posses many useful properties like anticancer, antibacterial, antifungal, anti–inflammatory, antimalarial and anti–diabetic activity. We report in this communication the synthesis and anticancer study of a number of novel chalcone sulfonamides. Our results indicate that the synthesis of chalcone sulfonami...
متن کاملSynthesis and anticancer activity assay of novel chalcone sulfonamide derivatives
Chalcones, or 1,3–diaryl–2–propen–1–ones, one of the major classes of natural products and posses many useful properties like anticancer, antibacterial, antifungal, anti–inflammatory, antimalarial and anti–diabetic activity. We report in this communication the synthesis and anticancer study of a number of novel chalcone sulfonamides. Our results indicate that the synthesis of chalcone sulfonami...
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BACKGROUND Rhodanines and quinazolinones have been reported to possess various pharmacological activities. RESULTS A novel series of twenty quinazolinone-based rhodanines were synthesized via Knoevenagel condensation between 4-[3-(substitutedphenyl)-3,4-dihydro-4-oxoquinazolin-2-yl)methoxy]substituted-benzaldehydes and rhodanine. Elemental and spectral analysis were used to confirm structures...
متن کاملSynthesis and Anticancer Activity Assay of Novel Chalcone-Sulfonamide Derivatives
Today Cancer remains to be one of the most deadly diseases in the world. Due to the potential anticancer activity of the chalcone and sulfonamide moieties, five novel hybrid compounds containing both structures have been designed and synthesized in 3 steps. The synthesized compounds were established on the basis of IR, 1H NMR, 13C NMR spectral data, and elemental analysis and also they were scr...
متن کاملSynthesis of novel 1,3,4-thiadiazole analogues with expected anticancer activity
Synthesis of substituted imidazo[2,1-b]-1,3,4-thiadiazoles 2a,b-6, substituted 1,3,4-thiadiazolo[3,2-a]pyrimidines 79 and 1,3-disubstituted thioureas 10a-e was reported. Structures of all synthesized compounds were elucidated using IR, NMR and mass spectroscopy. All the prepared derivatives were evaluated for their cytotoxic activity against tumor cell line A549 (Non-Small Cell Lung Cancer Cell...
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ژورنال
عنوان ژورنال: RSC Advances
سال: 2019
ISSN: 2046-2069
DOI: 10.1039/c9ra02950h